In a second publication by Jacoberger-Foissac et al, CD39 expression on CD8+ T cells was shown to suppress IFN γ production by T cells and transplantation of murine KPC tumors, myeloid expression of CD39 and CD73 and tumor expression of CD73 promoted polarization of myeloid cells to an M2 phenotype, which promoted PDAC growth and targeting both CD73 and CD39 significantly enhanced the anti-tumor T cell response. The gene discussed is CD8A; the disease is neoplasm.