CD8A and infection: First, immune cell distribution before and after HCMV infection for PBMCs in all samples (embedding STABLE and CLAD LTRs) (Figures 5A, B) indicates that the overall imprint of HCMV infection was a significant decrease in the frequency of B cells (~2-fold of the baseline before infection, p = 0.0124) and an increase in the frequency of CD8 T (~2-fold of the baseline before infection, p = 0.0024) and δ2−γδT (~5-fold of the baseline before infection, p < 0.0001) cells.