- tolerance induced (85% of the ALS group)- chimerism of B, monocytes and granulocytes appeared earlier than T cells- the tolerant graft skin had more Tregs- ↑ serum IL-1a, IL-2, TNF-α, IP-10, MCP-1, MCP-3 levels at rejecting recipients. The gene discussed is IL1A; the disease is amyotrophic lateral sclerosis.