CD8A and neoplasm: The cell density and percentage of CD8+PD-1+ cells seemed to be more present in structure with low stromal cells and high tumor cells but was found to be of no statistically significant difference between two types of structures (Figures 6C, D).The structure with abundant stromal cells and low tumor cells had higher percentage of CD8+PD-1− cells infiltration while the cell density of CD8+PD-1− showed no difference.