Also, we observed that patients with an overall high expression of PD-L1 and a strong tumor-infiltration by CTL showed a significantly better OS, PFS and response upon RCTx as compared to patients with expression below the median (see Figures 4, 5, Supplementary Figures 5–7, Supplementary Tables 7, 8, as well as Table 2). This evidence concerns the gene CD274 and neoplasm.