CHKA and breast cancer: A direct comparison between the breast cancer cell studies and the present study in GBM cells is not possible but overall our findings are consistent with the notion that the phosphorylation rate of Cho by choline kinase α is much faster than the transport rate of Cho, leading to a fast conversion of Cho to PC, and the a net production and increase in PC pool size that we observe (Katz-Brull et al., 1998).