On the contrary, a prior study by our group, evaluating 45 fetuses with left-CHD, found only modestly decreased PlGF in the left-CHD group compared to normal fetuses, and markedly decreased sFlt1 only in fetuses with univentricular left-CHD conferring a proangiogenic profile of PlGF and SFlt1 in the poor prognostic group (7). The gene discussed is PGF; the disease is coronary artery disorder.