PPARG and tuberculosis: While the changes in the peripheral compartment may not be an accurate reflection of the response that takes place at the injury site (D’Attilio et al., 2013), they bear some relationship with the extent of lung compromise, as specific anti-TB treatment induced a significant drop of PPARγ transcript expression and in proinflammatory mediators, possibly related to the lower bacterial burden (Sabiiti et al., 2020; Osei-Wusu et al., 2021).