To assess apoptosis induced by RV Wt1-5, flow cytometry was used to analyze the expression of pro-apoptotic proteins, including cleaved PARP-1, cytochrome-C, BAX, BID, cleaved caspase-3, cleaved caspase-9, as well as the anti-apoptotic protein Bcl-2 in gastric tumor cells and non-tumor cells inoculated with RV at different MOIs (MOI 0.2 or 0.8) after 12 hours of incubation. This evidence concerns the gene CYCS and neoplasm.