Different studies have shown that infection is favored by the formation of binding platforms between rotaviral proteins (VP5, VP8 and VP7) and multiple co-receptors overexpressed in tumor cells but not in non-tumor cells, such as integrins (α2β1, αVβ3, α4β1, and αxV2) and heat shock proteins (Hsp90, Hsp70, Hsp60, Hsp40, and Hsc70). The gene discussed is DNAJB1; the disease is neoplasm.