The evaluation of the ability to induce the expression of apoptotic proteins, including caspase 3, caspase 9, PARP, cytochrome C, BAX, BID, and Bcl-2, in gastric tumor tissue after 12 hours of RV infection showed early morphological changes associated with apoptosis, such as chromatin marginalization, nuclear condensation, and fragmentation. The gene discussed is CASP3; the disease is gastric neoplasm.