Using the GEPIA database, we revealed that KDM5C (Figure 6A), KDM8 (Figure 6C), and KDM4A (Figure 6D) were predictive genes for overall survival (OS), while only KDM5C (Figure S3) had prognostic value for disease-free survival (RFS) in HCC. The gene discussed is KDM4A; the disease is hepatocellular carcinoma.