CHI3L1 and neoplasm: Moreover, CIBERSORT analysis revealed elevated percentages in the tumor microenvironment of naïve B cells; Tregs; macrophages M0, M1, and M2; and neutrophils in the YKL-40 high-expression group, whereas in the YKL-40 low-expression group, elevated percentages of resting T-cell CD4 memory and monocytes were observed.