KRAS and neoplasm: As shown in Supplementary Table 5, the Cox regression model showed that ADC (compared with SCC), tumor size <1.5 cm, wild-type KRAS, and close distances from malignant cells to overall CD3 + T-cells, CD3 + CD8 + GZB + activated cytotoxic T-cells, CD3 + CD8 + CD45RO + memory cytotoxic T-cells, and overall CD20 + B-cells were associated with better OS.