In early life, immediately after the 8 week HF/LF diet feeding, we found that the HF diet is associated with 2.4-fold (p < 0.01), 3.3-fold (p < 0.01) and 1.8-fold (p < 0.01) increases in the transcriptional expression levels of Il-6, Ccl2 and Ccr2 in iMT, and that the protein level of CCL2 increased 1.8-fold (p < 0.01) in the HF group in iMT. The gene discussed is CCR2; the disease is hydrops fetalis.