CCND1 and hydrops fetalis: Interestingly, after switching to the normal diet for an additional 12 weeks up to 24 weeks of age, which is equivalent to young adulthood, the transcriptional expression of Cyclin D1 (p < 0.05) and Wnt 10b (p < 0.05) and the protein level of p-STAT3 had decreased in the HF group (Figure 5C,D).