In a large meta GWAS8, we identified several novel glioma risk-associated single nucleotide polymorphisms (SNPs), including rs11706832, which is located in intron 2 of the leucine-rich repeats and immunoglobulin-like domains protein 1 coding gene LRIG1 In another study, we found that rs11706832 is associated with the susceptibility for IDH1 mutated gliomas9. This evidence concerns the gene LRIG1 and central nervous system cancer.