Here, we evaluated in another group of 23 lean, non-diabetic, CHC patients infected with different genotypes, the hepatic expression of some of these factors known to be expressed in the liver (ANGPTL4, ANGPTL6, IGFBP7, SEPP1, visfastin, chemerin and vaspin) (Table 1 and Fig. 1a). This evidence concerns the gene IGFBP7 and cryohydrocytosis.