It is still controversial whether MA and salivary IPMN are separate entities or a disease spectrum, but because both MA and salivary IPMN are characterized by mucin production and the presence of activating AKT1 p.E17K gene mutation, IPMN is currently considered by some to be a low-grade or non-invasive subtype of MA [22–24]. This evidence concerns the gene AKT1 and microtia.