Among BAZ2A-TAM-dependent interacting proteins, we found topoisomerase 2A (TOP2A) and histone demethylase KDM1A, which have been previously implicated in aggressive PCa (Labbé et al, 2017; Liang et al, 2017; Sehrawat et al, 2018). This evidence concerns the gene TOP2A and posterior cortical atrophy.