Considering that congenital cataracts are one of the most consistent phenotypes linked to INPP5K mutations in humans (Osborn et al. 2017; Wiessner et al. 2017; Yousaf et al. 2017) the high expression of inpp5ka in lens cells found in the RNA scope experiments is also of note. This evidence concerns the gene INPP5K and early-onset non-syndromic cataract.