Three different genetically modified zebrafish lines were generated to determine the influence of the TATA/GATA regulatory site on the rate of initiation and penetrance of neuroblastoma: Tg(dβh:MYCN; dβh:EGFP; GATA/GATA), Tg(dβh:MYCN; dβh:EGFP; GATA/TATA), and Tg(dβh:MYCN; dβh:EGFP; TATA/TATA). Here, MYCN is linked to neuroblastoma.