Most ARVC candidate causal variants are located in five genes: plakoglobin (JUP), desmocollin‐2 (DSC2), desmoplakin (DSP), plakophilin‐2 (PKP2) and desmoglein‐2 (DSG2).115. This evidence concerns the gene DSP and arrhythmogenic right ventricular cardiomyopathy.