Another study confirmed the protective role of MetO reductase system to neurovascular inflammation in ischemic stroke, which attenuated ROS‐augmented NF‐κB activation in endothelial cells and protected against the oxidation of Met residues in the regulatory domain of calcium/calmodulin‐dependent protein kinase II (CaMKII).27 Here, NFKB1 is linked to ischemic stroke.