Although Hirotaka et al. found that dietary consumption of Lactobacillus-derived exopolysaccharide induced CCR6+ CD8+ T cells by CCL20-secreting tumor cells [56], Wang et al. also uncovered FOXO1 promoted the migration of M2 macrophages via CCL20 secretion in esophageal squamous cell carcinoma [57]. Here, FOXO1 is linked to esophageal squamous cell carcinoma.