Furthermore, in the present study, we mainly focused on MET and EGFR alterations, which are high-frequency typical genetic alterations in lung adenocarcinoma (LUAD) and are rarely detected in lung squamous cell carcinoma (LUSC).66 The molecular genomic alterations are quite different between LUAD and LUSC,66 the predominantly histologic subtypes of NSCLC. This evidence concerns the gene EGFR and non-small cell lung carcinoma.