CDH1 and non-small cell lung carcinoma: E-cadherin is a canonical epithelial hallmark, and loss of E-cadherin expression is a hallmark of EMT.42,43 We then tested both the E-cadherin level and SYK level in 102 NSCLC specimens by IHC to explore whether high SYK expression was associated with the epithelial phenotype in patient samples.