THAP11 and neoplasm: mESCs provided an ideal model for our studies because Ronin’s function has been best characterized in this cell type;50,61,62 they are genetically uncompromised, as opposed to tumor cell lines, and represent an authentic developmental in vitro model of the early embryonic “inner cell mass.” We found that Ronin was associated with the promoters of 10,916 genes (Table S1C) that showed a high degree of overlap with the much smaller set of previously described Ronin target genes (Figure S1A)21,50 and, as expected, were enriched with RBMs (Figure S1B; Table S1D).