1.35 GSC lines were analyzed, and two proteins galectin-1 and EGFR were overexpressed in response to TMZ resistance2. Level of SYMPK was found to be increased. SYMPK is associated with tumorigenesis and knock out of SYMPK inhibits tumor growth.3. SRSF2 is associated with chemoresistance. The gene discussed is EGFR; the disease is neoplasm.