They showed that CDKN1A, TP53I3, and PPM1D were upregulated by AL158206.1. Contrasting these findings, another work examining lncRNAs involved in the epithelial-mesenchymal-transition, associated with metastasis, identified AL158206.1 as one of four lncRNAs having the strongest negative impact on the survival of patients undergoing drug treatment of hepatocellular carcinoma (61). This evidence concerns the gene TP53I3 and hepatocellular carcinoma.