FGFR1 and neoplasm: As shown by the 3D MIP of micro-PET/CT imaging in Figure 5, FGFR1-high expression RT-112 xenograft mice had significantly higher tumor uptake (3.84 ± 0.17%ID/g) than that of FGFR1-low expression A549 (0.87 ± 0.08%ID/g), SNU-16 (0.66 ± 0.05%ID/g), Calu-3 (0.59 ± 0.08%ID/g) and RT-112 blocked xenografts (0.40 ± 0.02%ID/g), at 30 min post injection.