Furthermore, GO and KEGG pathway enrichment analyses showed enrichment of immune-related pathways, such as positive regulation of lymphocyte activation, B cell mediated immunity, chemokine activity, cytokine-cytokine receptor interaction, Th17 cell differentiation, Th1 and Th2 cell differentiation, T cell receptor signaling pathway, TNF signaling pathway, NF-κB signaling pathway, and PD-L1 expression and PD-1 checkpoint pathway in cancer. The gene discussed is CD274; the disease is cancer.