Then, we examined the expression levels of the nine genes based on the TCGA-KIRC cohort and found that the expression levels of BCL3, PABPC1L and PYCR1 in ccRCC samples were higher than those in normal samples, while the expression levels of NPNT, BACE2, MELTF and TOX3 in ccRCC samples were lower than those in normal samples (Figure 5C). The gene discussed is PYCR1; the disease is nonpapillary renal cell carcinoma.