A previous study employed a Fluorescence Ubiquitin Cell Cycle Indicator (FUCCI) cell-cycle sensor to show that adoptive transfer of CTLs induced G1-phase cell-cycle arrest of B16F10 tumor cells in an IFNG-dependent manner;15 however, the temporal evolution of this arrested state and correlation with the number of tumor-infiltrating CTLs was not explicitly quantified. This evidence concerns the gene IFNG and neoplasm.