The same trend was also not observed with diastolic blood pressure or among women [36]. In contrast, Brennan et al. found that patients with low CD4 < 50/μL count at ART initiation were at increased risk of incident hypertension compare to those with CD4 count of > 350/μL (hazard ratio, 1.25 CI: 1.03, 1.50) [37]. This evidence concerns the gene CD4 and hypertensive disorder.