The neutralizing SARS-CoV-2 antibody test results showed positivity of 83.6%, with the predominant positive rate in males (56%) among the healthy participants, whereas most RA patients were females and all showed positivity (100%) in the RA group. Neutralizing antibody titer (NAT) >50% was observed in 65% and 88.8% of young adults aged between 20 and 39 years among the healthy group and RA group, respectively. This evidence concerns the gene BRD2 and rheumatoid arthritis.