CCL22 and asthma: The AMPK signaling pathway is also activated in THP-1 cells in response to thymic stromal lymphopoietin, a cytokine involved in asthma pathogenesis, and mitophagy is subsequently promoted, which results in the enhanced expression of M2-related cytokines CCL-1 and CCL-22, as well as the reduced generation of M1-related cytokine CXCL-10; moreover, these effects are interdicted by the mitophagy inhibitor Mdivi-1 [46].