As shown in Figures 5(a) and 5(b), participants in the group with the high baseline serum MMP7 levels (>4.80 ng/ml) had a higher incidence of CHF (42%), and the risk of CHF greatly increased with the HR of 1.577 (95% CI 1.067-2.331, p = 0.02) by unadjusted analysis and of 1.595 (95% CI 1.023-2.488, p = 0.04) after adjusted analysis, compared to the lower baseline serum MMP7 group (Table 3). This evidence concerns the gene MMP7 and congestive heart failure.