PTK2 and melanoma: Other molecules identified to regulate cadherin expression in melanoma cells include: STAT3 and MEK, demonstrated to induce expression of N-cadherin (Vultur et al., 2014); FAK, knockdown of which is shown to reduce expression of E-cadherin (Pei et al., 2017); and Integrin Linked Kinase (ILK) which regulates N-cadherin membranous localisation through regulating its’ endocytosis and recycling (Gil et al., 2020).