Interestingly, the sequencing analysis on a family of NCMD patients shows a tandem duplication of PRDM13 gene and a partial copy of CCNC gene in MCDR1 locus, suggesting PRDM13 overexpression responsible for NCMD pathogenesis (Bowne et al., 2016). The gene discussed is CCNC; the disease is North Carolina macular dystrophy.