The age at diagnosis of IPF has been proved to be different also among carriers of mutations: TERT mutation carriers are diagnosed at an earlier age (mean of 51 years) relative to mutation carriers in TERC (mean of 58 years), RTEL1 (mean of 60 years), and PARN (mean of 65 years) (105). This evidence concerns the gene TERC and idiopathic pulmonary fibrosis.