On the other hand, Clarke et al. reported a decrease in serum IL-10 concentration following 28 days of 15 g/d fructans consumption among 30 healthy adults (54), and Dehghan et al. found a decrease in TNFα, CRP and lipopolysaccharide among women with T2D after 8 weeks of 10 g/d inulin supplementation together with a trend for increased IL-10 (55). This evidence concerns the gene TNF and type 2 diabetes mellitus.