INS and breast carcinoma: Other biomarkers like insulin, C-C motif chemokine ligand 2 (CCL2), transforming growth factor β 1(TGF-β1), and Treg-like molecule (Treg: Regulatory T cells) were also discussed in some of our reviewed publications, regarding their relevance primarily to breast cancer treatment (75, 76, 80, 83, 84, 88, 90).