The other study, conducted by Lahiji and colleagues, was an interesting randomized, triple-blind, placebo-controlled trial using a low calorie diet in obese breast cancer survivors who either received synbiotic supplementation (the combination of probiotics and prebiotics) or not and found hs-CRP as well as adiponectin levels can be lowered and likely indicate reduced rates of recurrence (93). This evidence concerns the gene ADIPOQ and breast carcinoma.