CXCL8 and breast carcinoma: In the other two studies, one confirmed a positive relationship between BMI and IL-8, but did not detail how the relationship could impact disease outcomes (63); while the other study explored whether inflammatory factors could mediate exercise effects on sleep quality for breast cancer survivors, but failed to find any significant impact of IL-8 levels, concluding this marker alone was not sufficient to result in sleep-associated outcomes (52).