SORD and distal hereditary motor neuropathy: In WGS, variants were detected in SORD (sorbitol dehydrogenase), which was recently identified as a causative gene of CMT or distal hereditary motor neuropathy (Fig. 4, Supplementary Table 7).24,26,27 In SORD, the c.757del variant is widely known as the most common pathogenic variant, and the majority of the cases reported so far are homozygous for this variant.