Mutations in the VCP gene were discovered as the cause of the autosomal dominant Inclusion Body Myopathy with PDB and Frontotemporal Dementia (IBMPFD), characterized by skeletal defects identical to the classical PDB (Kovach et al., 2001; Watts et al., 2004; Columbres et al., 2023). The gene discussed is VCP; the disease is inclusion body myopathy with Paget disease of bone and frontotemporal dementia.