Moreover, axon GO analysis of the DEG dataset of MS white matter lesions (Elkjaer et al., 2019) showed significant upregulation of transcripts involved in potassium homeostasis and glutamate receptor signaling (e.g., KCNJ6, KCNMA1, GRIN2B), particularly in chronic active MS lesions (Supplementary Figure 5C and Supplementary Table 5). Here, KCNMA1 is linked to myeloid sarcoma.