The results showed that upon lobaplatin treatment for 4 weeks, FUBP1‐overexpressing xenografts derived from two different osteosarcoma cell lines displayed higher expression of FUBP1 and Ki67 than the vector‐overexpressing mice and lower expression of cleaved caspase 3 than the control xenografts, whereas FUBP1 knockdown xenografts derived from two different osteosarcoma cell lines demonstrated weak FUBP1 and Ki67 staining and more cleaved caspase 3 activation (Figure 3E,F, Figure S6A,B). Here, CASP3 is linked to osteosarcoma.