Similarly, it was reported that mutation of FUBP1 might lead to lysine‐specific demethylase 1+8a deficiency and contribute to the tumorigenesis of glioma, suggesting the tumor‐suppressive effects of FUBP1,46 whereas competitive binding to circACTN4 could activate MYC transcription and facilitate tumor progression in breast cancer.33 This evidence concerns the gene FUBP1 and breast cancer.