NLRP3 and metabolic dysfunction-associated steatotic liver disease: Similarly, miR-7 levels were significantly elevated in NAFLD mouse model, triggering NLRP3 (NOD-like receptor protein 3) inflammasome activation and coronary microvascular endothelial hyperpermeability through regulation of lysosomal associated membrane protein 1 (LAMP1) and Cathepsin B (83).