KEGG pathway analysis revealed that the key targets were mainly involved in EGFR tyrosine kinase inhibitor resistance, the PPAR signaling pathway, proteoglycans in cancer, the relaxin signaling pathway, the HIF-1 signaling pathway, the FoxO signaling pathway, the ErbB signaling pathway, the estrogen signaling pathway, acute myeloid leukemia, the IL-17 signaling pathway, breast cancer, the AMP-activated protein kinase (AMPK) signaling pathway, the cell cycle, the cAMP signaling pathway, the Ras signaling pathway, and the TNF signaling pathway. The gene discussed is EGFR; the disease is breast carcinoma.