KCNA3 and ischemic stroke: This is an exciting observation that is in keeping with the time course of microglia/macrophages activation (Campanella et al., 2002; Hu et al., 2012) and KV1.3 expression after ischemic stroke, which starts to significantly increase between 2–5 days and peaks around day-8 after MCAO (Chen et al., 2018).