KCNA3 and ischemic stroke: We previously showed that blocking the voltage-gated potassium channel KV1.3, which is expressed on microglia and T cells, with our small molecule drug, PAP-1, results in reduced neuroinflammation without compromising the beneficial functions of the immune system such as phagocytosis of neuronal debris by microglia in two rodent models of ischemic stroke (Chen et al., 2018; Chen et al., 2021).