Ginsenoside R(e) markedly increased asthenozoospermic infertile human sperm motility by boosting NO production and NOS activity; however, the NOS inhibitor N (omega)-Nitro-L-arginine methyl ester (L-NAME) or NO scavenger N-Acetyl-L-cysteine (LNAC) inhibited the actions of Ginsenoside R (e) (Zhang et al., 2006). This evidence concerns the gene NOS1 and Infertility.