Besides, by observing the percentages of CD69+ cells in the peripheral blood lymphocytes of all eight NSCLC patients, we found that the percentages of CD69+ T cells and CD69+ NK cells were significantly higher in patients whose T/NK cells affected by PD-1 mAb (Yes) than those not affected by PD-1 mAb (No) (Fig. 1F). The gene discussed is CD69; the disease is non-small cell lung carcinoma.