We also found a significantly positive correlation between PD-L1+ECs (p = 0.002), PD-L1+TAMs (p = 0.020), PD-L1+ECs/ECs (p = 0.001), and PD-L1+TAMs/TAMs (p = 0.004) and the relative abundance of Lactobacillus in ESCC patients (Figures 4D, 5E, F). This evidence concerns the gene CD274 and esophageal squamous cell carcinoma.