Moreover, the percentage of splenic immune cells was decreased but the percentage of splenic erythroid cells was increased following the infection of P. yoelii NSM (Figures 1F, G), and most splenic erythroid cells expressed CD71 (Figure 1J), suggesting that the expansion of erythroid progenitor cells contributed mostly to splenomegaly in the P. yoelii NSM-infected mice. This evidence concerns the gene TFRC and infection.