IFNG and neoplasm: This APC-like behaviour of neutrophils has been observed in NSCL patients, where a subset of immature neutrophils (CD11b+ CD15hi CD10– CD16int/low) acquired the expression of MHCII and CD86 in response to GM-CSF and IFNγ and triggered a T cell-mediated anti-tumour response (175) (Figure 4C).